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Wham clusters all the applicant breakpoints and rounds their positions to the closest tenth base pair. The placement with the best go through support is claimed. Should the delicate-clipped consensus sequence is usually aligned for the putative breakpoint location utilizing the Smith-Waterman algorithm, the breakpoint is even further refined to The

Wham is created for paired-finish Illumina libraries with regular insert dimensions (~300bp-500bp). Wham integrates mate-pair mapping, break up examine mapping, comfortable-clipping, choice alignment and consensus sequence primarily based proof to predict SV breakpoints with single-nucleotide precision. Wham generates a mixed pileup (catalog of rea

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